Analytical Ultracentrifugation

In contrast to other methods used to analyze macromolecules, analytical ultracentrifugation (AUC) enables characterization of samples in their native state under biologically relevant solution conditions. AUC is the most versatile, rigorous and accurate technology available for determining the molecular weight, hydrodynamic and thermodynamic properties of a protein or other macromolecule. It can be used to investigate nearly any type of molecule or particle over a wide range of concentrations and in a diverse variety of solvents. For many research questions, there is no satisfactory analytical substitute for AUC.

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Stability of the Human Immunodeficiency Virus-1 Reverse Transcriptase Heterodimer Author: Jacob Lebowitz - University of Alabama, Birmingham, AL
Linearity of BSA Using Absorbance & Interference Optics Authors: Dean Clodfelter, M.S., |Chad Schwartz, Ph.D., Beckman Coulter Inc., 5350 Lakeview Parkway Dr., Indianapolis, IN 46268
Characterizing Insulin as a Biopharmaceutical Using Analytical Ultracentrifugation Author: Chad Schwartz, Ph.D., Dean Clodfelter, M.S. | Beckman Coulter, Inc., Indianapolis, IN 46268
High-Performance Automation and Centrifugation Preparation of Carbon Nanotubes for Analytical Ultracentrifugation Single-Walled Carbon Nanotubes (SWCNT) experienced increasing interest in the past 15 years for semiconductors, fuel cells, and biomedical applications
Comparing Data Quality & Optical Resolution of the Next Generation Optima AUC to the Proven ProteomeLab on a Model Protein System Authors: Julia P Luciano-Chadee - Beckman Coulter, Inc., Indianapolis, IN | Chad Schwartz Ph.D. - Beckman Coulter, Inc., Indianapolis, IN