Webinars, Life Sciences - Beckman Coulter


Cross-talk and Developmental Programs - A Key to Translational Stem Cell Biology Duration: 1 hour 31 minutes 13 seconds Cellular signaling mediated by extracellular membrane vesicles in the application of stem cells as therapeutics.
New Automation Strategies For Improving Sample Prep - The Analytical Laboratory Duration: 9 minutes 46 seconds This presentation by Michael Kowalski at Beckman Coulter Life Sciences covers automation of capillary electrophoresis and mass spectrometry workflows for the analytical laboratory. Learn how the Biomek 4000 Workstation enables accurate sample prep, essential for downstream applications. English
New Strategies to Improve Your CE-SDS Results: A Data-driven Perspective Duration: 56 minutes 3 seconds This webinar presents new strategies for improving your CD-SDS results including bioproduct analytical testing and a Biomek dilution program. This webinar is presented by Kevin Overstreet at Eli Lilly. English
Physical and Chemical Characterization of Nanoparticle Constructs Using the Analytical Ultracentrifuge Duration: 55 minutes 52 seconds Webinar covers physical and chemical characterization of nanoparticle constructs using analytical ultracentrifugation. Webinar is presented by Osman M Bakr from King Abdullah University of Science and Technology. English
Proteome Profiling of the Tumor Microenvironment: Role of Human Primary Fibroblasts Derived Exosomes in Oral Cancer Progression Duration: 50 minutes 14 seconds Proteomics analysis of tumor microenvironment focused on primary fibroblast-derived exosomes in oral cancer progression presented by Simone Principe from Princess Margaret Cancer Center University Health Network. English
Quantitative Determination of Reaction Stoichiometry, Interaction Energies, and Solute Masses Using Analytical Ultracentrifugation Duration: 1 hour 2 minutes 35 seconds Live broadcast covering applications of analytical ultracentrifugation (AUC). English
21 CFR Part 11 Data Integrity for Online TOC Instruments Duration: 34 minutes 39 seconds Beckman Coulter Life Sciences sponsors a video on 21 CFR Part 11 data integrity for online TOC instrumentation, presented by Tony Harrison English
European Pharmacopoeia EP2.2.44 Total Organic Carbon Duration: 28 minutes 41 seconds In this webinar, Tony Harrison of Beckman Coulter Life Sciences discusses European Pharmacopoeia and complete TOC oxidation for PW and WFI. English
Centrifugation Safety 1 (Japanese) Duration: 4 minutes 56 seconds Watch the Beckman Coulter Life Sciences video on Centrifugation Safety 1 (in Japanese) Japanese
Automated Assays For Protein Engineering, In Vitro And In Vivo, By Dr. Daniela Quaglia Duration: 59 minutes 1 seconds Educational webinar covering in vitro and in vivo examples of protein engineering: automation of in vivo and in vitro screening large libraries of enzyme variants.
Taking the Tricky Out of Automating NGS Sample Prep Duration: 14 minutes 30 seconds Presentation addresses challenging tasks in NGS (and other) workflows. Resources, demonstrated methods, instruments and techniques from Beckman Coulter also covered.
The Power of Automated Assay Optimization Duration: 39 minutes 11 seconds This webinar addresses the topic of automated assay optimization - what it is, why do it and benefits realized.
Recent Advances in Immunotherapy: Directing Cells to Address Disease Duration: 1 hour 10 minutes 2 seconds Watch this webinar on the recent advances in immunotherapy with a focus on directing cells to address disease, presented by Leena Gandhi MD PhD English
Analytical Methods to Measure Empty and Full AAV Particles Duration: 50 minutes 38 seconds Review around biophysical characterizing techniques and a focus on the use of analytical ultracentrifugation (AUC) for measuring empty and full AAV particles English
Contemporary Cell Staining and Imaging Tools for Screening Stem Cell-Derived Cardiomyocytes Duration: 59 minutes Webinar presented by Beckman Coulter, Molecular Devices and Cellular Dynamics covers image-based cardiomyocyte assays including a comprehensive toolbox and complete image solution for your image analysis needs.
Diversity of Cancer-Derived Extracellular Vesicles Duration: 59 minutes 59 seconds This webinar from Dr. Dolores Di Vizio covers extracellular vesicle heterogeneity, large oncosomes and potentials for biomarker development. English
Exploring Exosomes and the Tumor Microenvironment Duration: 1 hour 30 minutes 54 seconds Drs. David Lyden and Dr. Thomas Kislinger cover the topic of exosomes and the tumor microenvironment. English
Leveraging the Value of Automated High-Content Screening Duration: 13 minutes 34 seconds Learn how the ImageXpress^® Micro XLS high-content screening system and MetaXpress Software from Molecular Devices can be used to quickly analyze cells, processing 200,000 wells a day. The system is suitable for a range of sample types, beads, colonies, cells, tissue, whole animal and macrostructures. Originally presented at SLAS.
Reducing Human Errors in Pharmaceutical Manufacturing Quality Control Duration: 25 minutes 50 seconds Beckman Coulter Life Sciences sponsors a video on reducing human error in pharmaceutical quality control.
Large Scale Purification of RNA and RNA-based Nanoparticles by Preparative Ultracentrifugation Duration: 1 hour 1 minutes 45 seconds Webinar from Daniel Jasinski covers RNA nanotechnology in cancer therapy. RNA/RNA-based nanoparticle purification by ultracentrifugation including current technologies, different methods of ultracentrifugation, why large quantities of RNA are needed, methods for large-scale RNA purification. English
Is Immunotherapy Living up to its Promise? Duration: 1 hour 24 minutes 9 seconds Watch this webinar on the advancements and performance of immunotherapy, presented by Jill O'Donnell-Tormey and Alex Y. Huang English
Emitting Dye for Violet Laser Excitation with Krome Orange Duration: 29 minutes 50 seconds Krome Orange dye conjugates can be used on any flow cytometer equipped with violet excitation and appropriate emission filters. Data presented using Krome Orange conjugates of anti-human CD4, CD19 and CD45 in multicolor applications, including side scatter/CD45 gating and a 6-plus color stain. Krome Orange dye provides optimized second organic fluorochrome for violet excitation, enabling 10-color applications on the Gallios / Navios flow cytometer systems.
Data Insights for Automated Liquid Handling Duration: 14 minutes 40 seconds This webinar covers requirements for successful experiments, equipment and software to effectively enable data collection and elements involved in making a data plan to support data workflow in the lab.
Analysis of Particle Size Distributions by Analytical Ultracentrifugation Duration: 1 hour 2 minutes 22 seconds Helmut Cölfen discusses and particle size distributions by analytical ultracentrifugation. English
Automated Alternative to the Hanging Drop Method of Stem Cell Differentiation Duration: 55 minutes 53 seconds
Hematopoietic Bone Marrow Cell Sorting without Compromise Duration: 52 minutes 25 seconds Flow cytometry analysis and sorting are valuable techniques for studying distinct hematopoietic bone marrow populations. Webinar covers identification, isolation and purification of hematopoietic stem cells.
Centrifugation Safety (Japanese) Duration: 11 minutes 24 seconds Watch the Beckman Coulter Life Sciences video on Centrifugation Safety (Japanese) Japanese
Centrifugation Safety 2 Duration: 9 minutes 28 seconds Watch the Beckman Coulter Life Sciences video on Centrifugation Safety 2 (Japanese) Japanese
Simultaneous Dynamic Light Scattering and Zeta Potential Duration: 49 minutes 28 seconds Joshua Robinson presents this webinar on ultra-fast, simultaneous dynamic light scattering and zeta potential. Robinson discusses a case study of using carbon nanotubes in cancer therapy and an overview of dynamic light scattering (DLS) technology. English
Exosome Biogenesis and the Budding of Proteins and Viruses Duration: 1 hour 3 minutes 31 seconds Various models of exosome biogenesis have been proposed. The field however, lacks the robust mechanistic studies needed to obtain a molecular understanding of vesicle secretion. Learn how one lab has taken a cargo-based approach in which the team focuses on the cis-acting signals necessary and sufficient for the budding of specific proteins. Learn from Stephen J Gould why his work supports the hypothesis that the plasma membrane is a major site of exosome budding. English
Duration: xx minutes (x Videos at x minutes each) Russian
Analytical Ultracentrifugation in the Biopharmaceutical Industry Duration: 1 hour 4 minutes 34 seconds Dr. Alexander Bepperling focuses on the data analysis tools to achieve high precision when analyzing biopharmaceutical products due to an interest in minor species of about 1-2% usually comprising of the total protein content. He focuses on the data analysis done in SEDFIT. Learn how to set up continuous c(S) distribution analysis as implemented with SEDFIT software for enhanced reproducibility during a study of many batches of one protein. Also covers applications of sedimentation equilibrium (SE) for screening weak interactions and determining detergent binding to proteins. English
Basic Research Signaling Applications Duration: 55 minutes 39 seconds Basic signaling applications in life sciences research.
Flow Cytometry Data Analysis in a Flash Duration: 52 minutes 34 seconds An educational webinar on flow cytometry data analysis and how to overcome the analysis burden without a team of bio-statisticians at your disposal
Introduction to the New USP <787>: Subvisible Particulate Matter in Therapeutic Protein Injections Duration: 1 hour 6 minutes 30 seconds An introduction to USP <787>: Purpose and differences between <787> and <788>, visible vs subvisible particles, methods and technology.
Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry Duration: 1 hour 1 minute 3 seconds Beckman Coulter and 3D Biometrix cover topics including why culture cells in 3D, creating and feeding 3D cell cultures in hanging drop plates; reasons to automate 3D culture including examples of compound screening (flow cytometry & high content imaging) as well as automating a full screen.
Particle Counters Must Now be Calibrated With ISO 21501-4 Duration: 1 hour 2 minutes 56 seconds Overview on calibrating particle counters to 21501-4. English
Isolation of Extracellular Vesicles: Latest Advances and Challenges Duration: 58 minutes 30 seconds A webinar from Winston Patrick Kuo on advances and challenges in isolating extracellular (EV) vesicles. He highlights the need for streamlined, reliable and reproducible EV isolation for downstream studies. English
Accurate and Reproducible Measurement of Protein Zeta Potential Duration: 1 hour 4 minutes 12 seconds Webinar addresses methods accurate reproducible measurement of protein and nanoparticle zeta potential: DLS theory, electrophoretic mobility, modern light scattering technologies, protein and surfactant analysis.
Cellular Analysis Using the Coulter Principle Duration: 13 minutes 47 seconds Overview of the Coulter Principle, importance of changes in cell volume, overview of basic cell theory (how cells are sized and counted), methods for acquiring count and concentration data.
Does Your Protein Analysis Toolbox Need a Refresh? Duration: 1 hour 1 minute 44 seconds Dr. Rich Jones will guide you through the decision "Does Your Protein Analysis Toolbox Need a Refresh?" He discusses protein analysis methods using a framework of the life of a biotherapeutic. English
Monitoring Signal Transduction Pathways in Human Disease Duration: 54 minutes 46 seconds The availability of antibodies specifically reactive with phospho-epitopes characteristic of activated signaling proteins provides specific probes that can be used to monitor multiple signal transduction pathways simultaneously. However, successful use of these probes to intracellular targets has required the development of cell fixation and permeabilization techniques that preserve phospho-epitopes, plus cellular light scatter properties, plus cell surface CD molecules.
Advanced Flow Cytometric Analysis of Human T-Cell Memory Subsets Duration: 58 minutes 24 seconds Multi-color flow cytometry is a powerful tool to analyze the highly heterogeneous human T cell compartment
Automation-Enabled LC-MS Analysis of Biologics Duration: 14 minutes 50 seconds This is a webinar discussing the Analysis of Biologics
Seminar: Advanced Sensitivity and Resolution in Flow Cytometry through Innovation Duration: 1 hour 21 minutes 46 seconds J. Paul Robinson from Purdue University describes the innovations borrowed from the telecommunications industry that are being applied to flow cytometry. The unique collection of technologies are fueling the miniaturization of flow cytometry instruments while increasing the sensitivity and resolution of detected particles.
Avoid Pitfalls When Automating Cell Viability Counting for Biopharmaceutical Quality Control Duration: 48 minutes 17 seconds This educational webinar covers various modern automated cell counter technology, common pitfalls and how to avoid them. Includes discussion of the atuomated Trypan Blue cell counting method on the Vi-CELL XR. English
Automated High-Throughput and High-Content Analysis by Flow Cytometry Duration: 55 minutes 53 seconds Science of Flow Cytometry, Part 2.
The Science of Flow Cytometry Part 1 Duration: 53 minutes 44 seconds Learn how flow cytometry techniques are being used and how you can apply image and flow cytometry to your own research. Part 1.
Combined Use of Multiple Particle Characterization Technologies to Evaluate Targeted Liposomal Formulations Duration: 1 hour 6 minutes 46 seconds Multiple particle characterization technologies for evaluating targeted liposomal formulations webinar by Melvin E Klegerman. English
Cell Cycle Analysis by Quantitative Imaging Cytometry Duration: 54 minutes 59 seconds Imaging flow cytometry solutions from Beckman Coulter for automated, quantitative high-content, high-throughput cell cycle analysis.
Multi-Color Solution for Flow Cytometry Duration: 56 minutes 49 seconds Webinar. Empower your multicolor panel design with tools and techniques from Beckman Coulter.
Sample Prep for MS Duration: 45 minutes 39 seconds This webinar covers automated Biomek solutions for mass spec sample prep. English
Advances in Sedimentation Analysis by Dr. Borries Demeler Duration: 1 hour 8 minutes 46 seconds This presentation covers advances in sedimentation velocity (SV) analysis including methods for accurately characterizing heterogeneous systems at high resolution; approaches to extract rich information from SV experiments and techniques to measure the strength of macromolecular interactions with discrete binding models to whole boundary SV experiments in analytical ultracentrifugation. English
The Future of Liquid Handling Automation has Arrived Duration: 59 minutes 2 seconds First webinar in a three-part series introducing the new Biomek i-Series Automated Workstations. Two new liquid handlers designed to enable continuous innovation for tackling the ever-changing demands of life science research in mid- to high-throughput labs. Meet the product development team and learn more about new solutions. Q&A included. Additional webinars cover how i-Series solutions can accelerate a range of applications.
The Role of Exosomes in Inflammatory Disease - Pathogenesis and Treatment Duration: 1 hour 19 minutes 41 seconds This webinar covers the biology of exosomes and how they are involved in inflammatory diseases. Exosomes as biomarkers and therapeutic agents. English
Centrifugal Elutriation - Utility in the Flow Cytometry Laboratory Duration: 1 hour 4 minutes 57 seconds Dr. Peter Lopez will help you understand the utility of centrifugal elutriation in modern flow cytometry labs English
Multi-Sizing your Multi-Color for Panel Design Duration: 55 minutes 9 seconds Multi-parametric flow analysis provides tool for dissecting complex cell populations, identifying underlying mechanisms of disease and increasing test efficiencies. Optimal design critical for valid results.
Identifying and Isolating Stem Cells Through High-Speed Cell Sorting Duration: 54 minutes 48 seconds Webinar. A discussion of stem cells covering range of topics and cell types from E. Michael Meyer. English
Automating Continuous Cell Culture by Dr. Oliver Gassmann Duration: 42 minutes 20 seconds Learn how continuous cell culture can minimize tedious tasks associated with batch culture, best practices for keeping cells alive in an in vitro environment and how long-term processes can be streamlined with robust planning software.
Extracellular Vesicles Delivery and RNA Translation Duration: 1 hour 5 minutes 38 seconds This webinar by Charles Lai, PhD covers visualization and tracking for extracellular delivery and RNA translation using multiplexed reporters. English
Using Data to Drive Automated Screening and Effective Reporting Duration: 52 minutes 22 seconds Learn how to organize your data to drive results through your assay (miRNA screen) Includes summary of data management tools and data workflow cycle.
The Use of the Analytical Ultracentrifuge to Characterize Very Large Complex Biopharmaceuticals Duration: 1 hour 2 minutes 20 seconds This webinar covers the key attributes of AUC as a highly effective technique for characterizing viral vectors for viral gene therapy delivery systems English
Development and Production of Viral Vectors: Advances in Processes and Translation for Human Gene Therapy Duration: 46 minutes 34 seconds Understand the role viral vectors play in modern gene research and how ultracentrifugation is used to produce these key delivery systems English
Gallios Flow Cytometer Forward Angle Light Scatter Innovation Duration: 50 minutes 19 seconds In flow cytometry, the FALS (Forward Angle Light Scatter) detector collects scattered light from a particle that intersects with a laser and delivers information roughly proportional to the size of the particle. Learn more about the unprecedented detection capabilities of the Gallios flow cytometer.
Diversity of Extracellular Vesicles and Their Cargo in Cell-To-Cell Communication Duration: 1 hour 2 minutes 56 seconds Dr. Jan Lötvall discusses the study of extracellular vesicles and their relevance for cell-to-cell communication and how they have been implicated in several ways in disease progression. Understand the wide diversity of extracellular vesicles, with diverse morphology according to electron microscopy studies and difference in RNA and protein cargo according to bioinformatics analyses. English
Optimizing Quality Control Electronic Records for 21 CFR Part 11 Compliance Duration: 45 minutes 58 seconds In this video, Beckman Coulter Product Manager Tony Harrison covers quality control records and 21 CFR Part 11, manual and electronic SOPs, final product QC, cleanroom environmental monitoring records and QC instrumentation electronic records. English
Particle Size Distribution for Cement using Laser Diffraction Duration: 48 minutes 2 seconds Importance of particle sizing in cement production. Using laser diffraction. Not all laser diffraction instruments are equal. Webinar presented by Edward Hoff. English
Pushing the Boundaries of Nanoparticle Characterization Duration: 49 minutes 28 seconds Simultaneous dynamic light scattering and zeta potential. Using carbon nanotubes in Cancer therapy and characterization of nanotubes. Beckman Coulter Life Sciences presents a video on pushing the boundaries of nanoparticle characterization with ultra-fast, simultaneous dynamic light scattering and zeta potential. English
Rethinking Data Analysis for Flow Cytometry with Kaluza 1.1 Software Duration: 55 minutes 56 seconds Quickly and efficiently analyze multi-color, multi-parametric high content data generated by today's flow cytometers with revolutionary Kaluza analysis software.
Microvesicle Detection and Cell Sorting Duration: 57 minutes 11 seconds Webinar presented by Vasilis Toxavidis, MChS, HCPR Resource Director, Beth Israel Deaconess Medical Center Flow Cytometry Core Facility, Harvard Stem Cell Institute and John Tigges, Beth Israel Deaconess Medical Center Flow Cytometry Core Facility, Harvard Stem Cell Institute.
Particle Size Characterization by Laser Diffraction Analysis in Geoscience and Soil Science Duration: 56 minutes 39 seconds Application of particle size characterization in the field of geoscience and soil science. Includes several case studies, discussion of preparation and treatment of materials prior to measurement and importance of subpopulations in wide particle size distributions. Dr. Björn Machalett gives this webinar. English
Advanced Process Quality Control and Outlier Detection with Discrete Particle Analysis Duration: 47 minutes 29 seconds Avanced process quality control and outlier detection with discrete particle analysis.Covers basic principles, the Coulter Principle and chemical/material applications. English
High-Performance Exosome Purification and Characterization via automated Density Gradient Duration: 1 hour 19 seconds Rapid, accurate exosome purification and sizing with density gradient, ultracentrifugation and dynamic light scattering by Joshua T. Robinson. English
Particle Size and Associated Sedimentary Processes on Wetland Gain and Loss in the Mississippi River Delta Duration: 1 hour 3 minutes 38 seconds Influence of particle size and associated sedimentary processes on wetland gain and loss in the Mississippi River Delta. This webinar is presented by Alexander S Kolker at Louisiana Unviersities Marine Consortium. English
ICH Q2 Validating a TOC Analyser with the QbD1200 Duration: 27 minutes, 10 seconds Hear Tony Harrison discuss validating a pharmaceutical grade TOC laboratory analyzer to the International Committee on Harmonization procedure ICH Q2. ICH Q2 contains guidance on how to ensure that a TOC analyzer is fit for purpose and for providing batch release data. English
Characterization of Extracellular Vesicles with Nanoscale Flow Cytometry Duration: 49 minutes 14 seconds How to set up a flow cytometer for nanoparticle analyses
Overcoming the Hurdles of Density Gradient Ultracentrifugation for Optimized Gene Therapy Purification Workflows Duration: 51 minutes 6 seconds Learn about the various types of density gradients techniques, how they are used, and how to get started as well as how to design and optimize a density gradient ultracentrifugation workflow, with AAV and plasmid DNA purification as examples. English
The Revised ISO 14644-1 Changes Classification and Monitoring Methods Duration: 1 hour 16 minutes 55 seconds ISO 14644-1: Impacts on classification methods and monitoring strategies presented by Joe Gecsey.
ACFTD Discontinuance and the HIAC 8011+ and HIAC PODS+ Duration: 41 minutes, 55 seconds Air Cleaner Fine Test Dust (ACFTD) was used by the hydraulics industry as a calibration medium for petroleum based liquid particle counters for many years and served as the basis for generating NAS 1638 and ISO 4402 cleanliness codes. Find out what to do now that ACFTD has been discontinued. Hear Bill F. Bars, Senior Applications Scientist, discuss ACFTD discontinuance in regards to the HIAC 8011+ and HIAC PODS+ liquid particle counters. English
Goldilocks & the Three Cells: The Art of Monitoring & Managing Cell Cultures Duration: 37 minutes 36 seconds Too acidic? Overly alkaline? Or just right? Culturing cells is a subtle, dynamic process that requires constant monitoring and adjustment to maintain a “biological Goldilocks zone (BGZ).” This zone represents the delicate balance between cells, cell media, reagents and growth conditions. In this webinar, Dr. Lenz explains how cell volume data can be used as a surrogate means of monitoring other aspects of cell viability related to the “BGZ.” In particular, he examines how monitoring cell volume can be helpful for assessing cell activation and proliferation – a critical factor in CAR-T cell research. After concluding his remarks, Dr. Lenz participates in a brief but informative Q&A with webinar attendees. (Total time: 37:35) English
Looking Under the Hood: Getting Started with the Optima AUC Duration: 56 minutes 5 seconds n the webinar we discussed the fundamentals of analytical ultracentrifugation and looked at a few sample applications.
Webinar: An Intro to Characterization of Biomolecules Using AUC Duration: 60 minutes 13 seconds Analytical Ultracentrifugation (AUC) is one of the most powerful biophysical tools used today for the characterization of biological samples ranging from small drug molecules to intact viruses, vesicles and microparticles
Duration: xx minutes (x Videos at x minutes each) Russian
Evolution in the Manufacturing of Cellular Therapies Duration: xx minutes (x Videos at x minutes each) Lessons learned and current solutions Immunotherapy is a powerful treatment that harnesses the body’s immune system in the fight against cancer. With optimized cell therapy, the result is an expanded population of T cells primed to recognize and eradicate malignant tumor cells that would otherwise escape immune detection. The webinar will discuss how cellular therapies have evolved, lessons learned through the evolution and current solutions available today. Learning Objectives: Commercialization of manufacturing- preparing a CAR Garage, lessons learned and how does it impact the patient. Automated functional testing- fully integrated unit operations taking the art out of science!
Applications of Counterflow Centrifugal Elutriation CCE Duration: 40 minutes Applications of Counterflow Centrifugal Elutriation CCE and the history and principle behind it English
Contamination Control in the Hydraulic Industry Duration: 51 minutes 36 seconds Rob Fish presents how contamination affects hydraulics and what you can do about it. English
The Science of Flow Cytometry Part 2 Duration: 55 minutes 53 seconds Learn how flow cytometry techniques are being used and how you can apply image and flow cytometry to your own research. Part 2.
Laser Cytometry in Biomedical Analysis Duration: 58 minutes 19 seconds Image cytometry (also termed laser scanning cytometry) represents a unique hybrid technology between flow cytometry and traditional fluorescent microscopy. Learn more about the science and vast biomedical applications of quantitative analytical cytology using laser-activated detection.
Diamond-Based Nanomedicine for Enhanced Cancer Treatment and Imaging Duration: 58 minutes 12 seconds This webinar covers the unique attributes of diamond-based nanoparticles and why they are effective when imaging for cancer and drug delivery as well as their in-vitro and in-vivo applications.
Analytical Ultracentrifugation of Carbon Nanotubes Duration: 1 hour 21 minutes 26 seconds Sedimentation velocity (SV) experiments on dispersed nanoparticles present an effective means for determining the hard-to-evaluate properties of nanoparticles. This webinar by Dr. Jeffrey Fagan focuses on leveraging the capabilities of SV methods for characterizing single-wall carbon nanotubes (SWCNTs). Results detailing the use of density contrast techniques on the characterization of the interfacial layer on specific SWCNT species demonstrate the power of analytical ultracentrifugation to resolve this interfacial layer. Dr. Jeffrey Fagan is from the National Institute of Standards and Technology and discusses the analytical ultracentrifugation of single-wall carbon nanotubes, as well as provides background information to apply to other nanoparticles. Dr. Fagan begins with an introduction to analytical ultracentrifugation and a quick explanation of single-wall carbon nanotubes. He discusses what we can characterize with the AUC technique, problems and pitfalls we might encounter, and a discussion about how those pitfalls can differ for different nanoparticles. Lastly, he provides two technical examples using the AUC measurement technique on single-wall carbon nanotubes. English
How Stem Cells Speak with Immune Cells Duration: 1 hour 8 minutes 33 seconds Watch this webinar from Stefan Pluchino on how stem cells signal to the host immune system English
ICH Q2 Validation of On-line TOC Analyzers Duration: 23 minutes 59 seconds In this webinar, Tony Harrison of Beckman Coulter Life Sciences discusses the validation of on-line TOC analyzers for product release testing using ICH Q2. English
The Art of Sorting for Advancing Cytometry Duration: 55 minutes 27 seconds Learn the basic elements for successful sorting: droplet breakoff, particle detection, sort decisions/delay, droplet charging and deflection.
Analytical Ultracentrifugation For Structural Analysis - Proteins and Macromolecular Complexes Duration: 1 hour 21 minutes 9 seconds The analytical ultracentrifugation (AUC) technique is presented as a highly effective method for characterizing the structural aspects of macromolecules and as a quantitative technique that provides access to detailed thermodynamic characterization of a system under study. Also learn how AUC enables study of conformational changes and complex formation in physiologically relevant buffers. Dr. Andy Herr provides a great overview of analytical ultracentrifugation (AUC). He discusses basic theory of AUC, sedimentation velocity, sedimentation equilibrium, and more. English
Analytical Ultracentrifugation in Nanoparticle Analysis Duration: 1 hour 1 minutes 43 seconds Joshua Robinson covers the utility of fractionation in the investigation of complex mixtures and polydisperse samples as well as versatility of analytical ultracentrifugation (AUC) for colloid chemistry. He quickly reviews analytical ultracentrifugation (AUC) theory, then discusses deconstructing nano-constructs and how AUC has been used in recent literature to really probe the underlying structure of nano-constructs, nanomaterials. Other topics covered include nanoparticle sample preparation, as well as Beckman Coulter's research and future perspectives. English
Exploring the Stoichiometry of Macromolecular Complexes Using Multi-Signal Sedimentation Velocity Analytical Ultracentrifugation Duration: 1 hour 14 minutes 43 seconds This webinar by Dr. Chad Brautigam covers the stoichiometry of macromolecule complexes by multi-signal sedimentation velocity analytical ultracentrifugation. English
Isolation and Characterization of Exosomes and Ectosomes Duration: 1 hour 12 minutes 46 seconds Presentation from Suresh Mathivanan at La Trobe University covers practical insights and experience relating to exosome and ectosome isolation & characterization. English
Analysis of Cell Biochemical Processes from First Principles to Cytometry Duration: 1 hour 3 minutes 9 seconds Cell cycle progression/biochemical processes. Analysis by flow cytometry.
Dendritic Cells Sorting Duration: 59 minutes 1 second Russian
Duration: xx minutes (x Videos at x minutes each) Japanese
Extracellular Vesicle Isolation by Flow Cytometric Sorting and Characterization by Analytical Ultra-Centrifugation and Dynamic Light Scatter Duration: 53 minutes 24 seconds This presentation covers extracellular vesicle isolation via flow cytometric sorting and characterization by AUC and dynamic light scatter. English
Quantifying Protein Aggregates by Sedimentation Velocity Duration: 51 minutes 28 seconds Webinar covering protein aggregate quantification by sedimentation velocity by Michael Stoner PhD of Amgen - PART I. AUC instrumentation & protein aggregate quantification; PART II. Size exclusion chromatography vs sedimentation velocity; PART III. Simulation as a tool for understanding results. English
Automation of PCR Setup and AMPure XP Purification using the Biomek 4000 Workstation Duration: 33 minutes 55 seconds This webinar covers PCR Setup and AMPure XP cleanup applications using the Biomek 4000.
Avoiding the Perils of Hidden Requirements Duration: 14 minutes 7 seconds This video presentation covers important considerations and sometimes overlooked requirements when selecting an integration partner.
Duration: xx minutes (x Videos at x minutes each) Russian
Choosing the Right TOC Analyzer for a Pharmaceutical QC Laboratory Duration: 58 minutes, 9 seconds Hear Tony Harrison discuss the regulations for total organic carbon in pharmaceutical water, the typical measurement technologies that are used by TOC analyzers in pharmaceutical water analysis quality control, and lastly hear the introduction of a lab quality control analyzer that has been optimized for laboratory QC applications. English
Initial Evaluation of the ClearLLab 10C System in the Immunophenotyping of Leukemia and Non Hodgkin Lymphoma Duration: 42 minutes 59 seconds In this webinar understand the process for routine cocktail selection and preparation, describe the key concepts in the ClearLLab 10 color system design, demonstrate using case studies the applicability of ClearLLab reagents and evaluate the results of the clinical accuracy study.

Cross-talk and Developmental Programs - A Key to Translational Stem Cell Biology

Duration: 1 hour 31 minutes 13 seconds Cellular signaling mediated by extracellular membrane vesicles in the application of stem cells as therapeutics.

New Automation Strategies For Improving Sample Prep - The Analytical Laboratory

Duration: 9 minutes 46 seconds This presentation by Michael Kowalski at Beckman Coulter Life Sciences covers automation of capillary electrophoresis and mass spectrometry workflows for the analytical laboratory. Learn how the Biomek 4000 Workstation enables accurate sample prep, essential for downstream applications.

English

New Strategies to Improve Your CE-SDS Results: A Data-driven Perspective

Duration: 56 minutes 3 seconds This webinar presents new strategies for improving your CD-SDS results including bioproduct analytical testing and a Biomek dilution program. This webinar is presented by Kevin Overstreet at Eli Lilly.

English

Physical and Chemical Characterization of Nanoparticle Constructs Using the Analytical Ultracentrifuge

Duration: 55 minutes 52 seconds Webinar covers physical and chemical characterization of nanoparticle constructs using analytical ultracentrifugation. Webinar is presented by Osman M Bakr from King Abdullah University of Science and Technology.

English

Proteome Profiling of the Tumor Microenvironment: Role of Human Primary Fibroblasts Derived Exosomes in Oral Cancer Progression

Duration: 50 minutes 14 seconds

Proteomics analysis of tumor microenvironment focused on primary fibroblast-derived exosomes in oral cancer progression presented by Simone Principe from Princess Margaret Cancer Center University Health Network.

English

Quantitative Determination of Reaction Stoichiometry, Interaction Energies, and Solute Masses Using Analytical Ultracentrifugation

Duration: 1 hour 2 minutes 35 seconds Live broadcast covering applications of analytical ultracentrifugation (AUC).

English

21 CFR Part 11 Data Integrity for Online TOC Instruments

Duration: 34 minutes 39 seconds Beckman Coulter Life Sciences sponsors a video on 21 CFR Part 11 data integrity for online TOC instrumentation, presented by Tony Harrison

English

European Pharmacopoeia EP2.2.44 Total Organic Carbon

Duration: 28 minutes 41 seconds In this webinar, Tony Harrison of Beckman Coulter Life Sciences discusses European Pharmacopoeia and complete TOC oxidation for PW and WFI.

English

Centrifugation Safety 1 (Japanese)

Duration: 4 minutes 56 seconds Watch the Beckman Coulter Life Sciences video on Centrifugation Safety 1 (in Japanese)

Japanese

Automated Assays For Protein Engineering, In Vitro And In Vivo, By Dr. Daniela Quaglia

Duration: 59 minutes 1 seconds Educational webinar covering in vitro and in vivo examples of protein engineering: automation of in vivo and in vitro screening large libraries of enzyme variants.

English

Analytical Methods to Measure Empty and Full AAV Particles

Duration: 50 minutes 38 seconds Review around biophysical characterizing techniques and a focus on the use of analytical ultracentrifugation (AUC) for measuring empty and full AAV particles

English

Contemporary Cell Staining and Imaging Tools for Screening Stem Cell-Derived Cardiomyocytes

Duration: 59 minutes Webinar presented by Beckman Coulter, Molecular Devices and Cellular Dynamics covers image-based cardiomyocyte assays including a comprehensive toolbox and complete image solution for your image analysis needs.

Diversity of Cancer-Derived Extracellular Vesicles

Duration: 59 minutes 59 seconds This webinar from Dr. Dolores Di Vizio covers extracellular vesicle heterogeneity, large oncosomes and potentials for biomarker development.

English

Exploring Exosomes and the Tumor Microenvironment

Duration: 1 hour 30 minutes 54 seconds Drs. David Lyden and Dr. Thomas Kislinger cover the topic of exosomes and the tumor microenvironment.

English

Leveraging the Value of Automated High-Content Screening

Duration: 13 minutes 34 seconds Learn how the ImageXpress^® Micro XLS high-content screening system and MetaXpress Software from Molecular Devices can be used to quickly analyze cells, processing 200,000 wells a day. The system is suitable for a range of sample types, beads, colonies, cells, tissue, whole animal and macrostructures. Originally presented at SLAS.

Reducing Human Errors in Pharmaceutical Manufacturing Quality Control

Duration: 25 minutes 50 seconds Beckman Coulter Life Sciences sponsors a video on reducing human error in pharmaceutical quality control.

Large Scale Purification of RNA and RNA-based Nanoparticles by Preparative Ultracentrifugation

Duration: 1 hour 1 minutes 45 seconds Webinar from Daniel Jasinski covers RNA nanotechnology in cancer therapy. RNA/RNA-based nanoparticle purification by ultracentrifugation including current technologies, different methods of ultracentrifugation, why large quantities of RNA are needed, methods for large-scale RNA purification.

English

Is Immunotherapy Living up to its Promise?

Duration: 1 hour 24 minutes 9 seconds Watch this webinar on the advancements and performance of immunotherapy, presented by Jill O'Donnell-Tormey and Alex Y. Huang

English

Emitting Dye for Violet Laser Excitation with Krome Orange

Duration: 29 minutes 50 seconds Krome Orange dye conjugates can be used on any flow cytometer equipped with violet excitation and appropriate emission filters. Data presented using Krome Orange conjugates of anti-human CD4, CD19 and CD45 in multicolor applications, including side scatter/CD45 gating and a 6-plus color stain. Krome Orange dye provides optimized second organic fluorochrome for violet excitation, enabling 10-color applications on the Gallios / Navios flow cytometer systems.

Data Insights for Automated Liquid Handling

Duration: 14 minutes 40 seconds This webinar covers requirements for successful experiments, equipment and software to effectively enable data collection and elements involved in making a data plan to support data workflow in the lab.

Analysis of Particle Size Distributions by Analytical Ultracentrifugation

Duration: 1 hour 2 minutes 22 seconds Helmut Cölfen discusses and particle size distributions by analytical ultracentrifugation.

English

Automated Alternative to the Hanging Drop Method of Stem Cell Differentiation

Duration: 55 minutes 53 seconds

Hematopoietic Bone Marrow Cell Sorting without Compromise

Duration: 52 minutes 25 seconds Flow cytometry analysis and sorting are valuable techniques for studying distinct hematopoietic bone marrow populations. Webinar covers identification, isolation and purification of hematopoietic stem cells.

Centrifugation Safety (Japanese)

Duration: 11 minutes 24 seconds Watch the Beckman Coulter Life Sciences video on Centrifugation Safety (Japanese)

Japanese

Centrifugation Safety 2

Duration: 9 minutes 28 seconds Watch the Beckman Coulter Life Sciences video on Centrifugation Safety 2 (Japanese)

Japanese

Simultaneous Dynamic Light Scattering and Zeta Potential

Duration: 49 minutes 28 seconds Joshua Robinson presents this webinar on ultra-fast, simultaneous dynamic light scattering and zeta potential. Robinson discusses a case study of using carbon nanotubes in cancer therapy and an overview of dynamic light scattering (DLS) technology.

English

Exosome Biogenesis and the Budding of Proteins and Viruses

Duration: 1 hour 3 minutes 31 seconds Various models of exosome biogenesis have been proposed. The field however, lacks the robust mechanistic studies needed to obtain a molecular understanding of vesicle secretion. Learn how one lab has taken a cargo-based approach in which the team focuses on the cis-acting signals necessary and sufficient for the budding of specific proteins. Learn from Stephen J Gould why his work supports the hypothesis that the plasma membrane is a major site of exosome budding.

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Analytical Ultracentrifugation in the Biopharmaceutical Industry

Duration: 1 hour 4 minutes 34 seconds Dr. Alexander Bepperling focuses on the data analysis tools to achieve high precision when analyzing biopharmaceutical products due to an interest in minor species of about 1-2% usually comprising of the total protein content. He focuses on the data analysis done in SEDFIT. Learn how to set up continuous c(S) distribution analysis as implemented with SEDFIT software for enhanced reproducibility during a study of many batches of one protein. Also covers applications of sedimentation equilibrium (SE) for screening weak interactions and determining detergent binding to proteins.

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Basic Research Signaling Applications

Duration: 55 minutes 39 seconds Basic signaling applications in life sciences research.

Flow Cytometry Data Analysis in a Flash

Duration: 52 minutes 34 seconds

An educational webinar on flow cytometry data analysis and how to overcome the analysis burden without a team of bio-statisticians at your disposal

Introduction to the New USP <787>: Subvisible Particulate Matter in Therapeutic Protein Injections

Duration: 1 hour 6 minutes 30 seconds An introduction to USP <787>: Purpose and differences between <787> and <788>, visible vs subvisible particles, methods and technology.

Automated 3D Cell Culture and Screening by Imaging and Flow Cytometry

Duration: 1 hour 1 minute 3 seconds Beckman Coulter and 3D Biometrix cover topics including why culture cells in 3D, creating and feeding 3D cell cultures in hanging drop plates; reasons to automate 3D culture including examples of compound screening (flow cytometry & high content imaging) as well as automating a full screen.

Particle Counters Must Now be Calibrated With ISO 21501-4

Duration: 1 hour 2 minutes 56 seconds Overview on calibrating particle counters to 21501-4.

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Isolation of Extracellular Vesicles: Latest Advances and Challenges

Duration: 58 minutes 30 seconds A webinar from Winston Patrick Kuo on advances and challenges in isolating extracellular (EV) vesicles. He highlights the need for streamlined, reliable and reproducible EV isolation for downstream studies.

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Accurate and Reproducible Measurement of Protein Zeta Potential

Duration: 1 hour 4 minutes 12 seconds Webinar addresses methods accurate reproducible measurement of protein and nanoparticle zeta potential: DLS theory, electrophoretic mobility, modern light scattering technologies, protein and surfactant analysis.

Cellular Analysis Using the Coulter Principle

Duration: 13 minutes 47 seconds Overview of the Coulter Principle, importance of changes in cell volume, overview of basic cell theory (how cells are sized and counted), methods for acquiring count and concentration data.

Does Your Protein Analysis Toolbox Need a Refresh?

Duration: 1 hour 1 minute 44 seconds Dr. Rich Jones will guide you through the decision "Does Your Protein Analysis Toolbox Need a Refresh?" He discusses protein analysis methods using a framework of the life of a biotherapeutic.

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Monitoring Signal Transduction Pathways in Human Disease

Duration: 54 minutes 46 seconds The availability of antibodies specifically reactive with phospho-epitopes characteristic of activated signaling proteins provides specific probes that can be used to monitor multiple signal transduction pathways simultaneously. However, successful use of these probes to intracellular targets has required the development of cell fixation and permeabilization techniques that preserve phospho-epitopes, plus cellular light scatter properties, plus cell surface CD molecules.

Advanced Flow Cytometric Analysis of Human T-Cell Memory Subsets

Duration: 58 minutes 24 seconds Multi-color flow cytometry is a powerful tool to analyze the highly heterogeneous human T cell compartment

Automation-Enabled LC-MS Analysis of Biologics

Duration: 14 minutes 50 seconds This is a webinar discussing the Analysis of Biologics

Seminar: Advanced Sensitivity and Resolution in Flow Cytometry through Innovation

Duration: 1 hour 21 minutes 46 seconds J. Paul Robinson from Purdue University describes the innovations borrowed from the telecommunications industry that are being applied to flow cytometry. The unique collection of technologies are fueling the miniaturization of flow cytometry instruments while increasing the sensitivity and resolution of detected particles.

Avoid Pitfalls When Automating Cell Viability Counting for Biopharmaceutical Quality Control

Duration: 48 minutes 17 seconds

This educational webinar covers various modern automated cell counter technology, common pitfalls and how to avoid them. Includes discussion of the atuomated Trypan Blue cell counting method on the Vi-CELL XR.

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Automated High-Throughput and High-Content Analysis by Flow Cytometry

Duration: 55 minutes 53 seconds Science of Flow Cytometry, Part 2.

The Science of Flow Cytometry Part 1

Duration: 53 minutes 44 seconds Learn how flow cytometry techniques are being used and how you can apply image and flow cytometry to your own research. Part 1.

Combined Use of Multiple Particle Characterization Technologies to Evaluate Targeted Liposomal Formulations

Duration: 1 hour 6 minutes 46 seconds Multiple particle characterization technologies for evaluating targeted liposomal formulations webinar by Melvin E Klegerman.

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Cell Cycle Analysis by Quantitative Imaging Cytometry

Duration: 54 minutes 59 seconds Imaging flow cytometry solutions from Beckman Coulter for automated, quantitative high-content, high-throughput cell cycle analysis.

Multi-Color Solution for Flow Cytometry

Duration: 56 minutes 49 seconds Webinar. Empower your multicolor panel design with tools and techniques from Beckman Coulter.

Sample Prep for MS

Duration: 45 minutes 39 seconds This webinar covers automated Biomek solutions for mass spec sample prep.

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Advances in Sedimentation Analysis by Dr. Borries Demeler

Duration: 1 hour 8 minutes 46 seconds This presentation covers advances in sedimentation velocity (SV) analysis including methods for accurately characterizing heterogeneous systems at high resolution; approaches to extract rich information from SV experiments and techniques to measure the strength of macromolecular interactions with discrete binding models to whole boundary SV experiments in analytical ultracentrifugation.

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The Future of Liquid Handling Automation has Arrived

Duration: 59 minutes 2 seconds First webinar in a three-part series introducing the new Biomek i-Series Automated Workstations. Two new liquid handlers designed to enable continuous innovation for tackling the ever-changing demands of life science research in mid- to high-throughput labs. Meet the product development team and learn more about new solutions. Q&A included. Additional webinars cover how i-Series solutions can accelerate a range of applications.

The Role of Exosomes in Inflammatory Disease - Pathogenesis and Treatment

Duration: 1 hour 19 minutes 41 seconds This webinar covers the biology of exosomes and how they are involved in inflammatory diseases. Exosomes as biomarkers and therapeutic agents.

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Centrifugal Elutriation - Utility in the Flow Cytometry Laboratory

Duration: 1 hour 4 minutes 57 seconds Dr. Peter Lopez will help you understand the utility of centrifugal elutriation in modern flow cytometry labs

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Multi-Sizing your Multi-Color for Panel Design

Duration: 55 minutes 9 seconds

Multi-parametric flow analysis provides tool for dissecting complex cell populations, identifying underlying mechanisms of disease and increasing test efficiencies. Optimal design critical for valid results.

Identifying and Isolating Stem Cells Through High-Speed Cell Sorting

Duration: 54 minutes 48 seconds Webinar. A discussion of stem cells covering range of topics and cell types from E. Michael Meyer.

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Automating Continuous Cell Culture by Dr. Oliver Gassmann

Duration: 42 minutes 20 seconds Learn how continuous cell culture can minimize tedious tasks associated with batch culture, best practices for keeping cells alive in an in vitro environment and how long-term processes can be streamlined with robust planning software.

Extracellular Vesicles Delivery and RNA Translation

Duration: 1 hour 5 minutes 38 seconds This webinar by Charles Lai, PhD covers visualization and tracking for extracellular delivery and RNA translation using multiplexed reporters.

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Using Data to Drive Automated Screening and Effective Reporting

Duration: 52 minutes 22 seconds Learn how to organize your data to drive results through your assay (miRNA screen) Includes summary of data management tools and data workflow cycle.

The Use of the Analytical Ultracentrifuge to Characterize Very Large Complex Biopharmaceuticals

Duration: 1 hour 2 minutes 20 seconds This webinar covers the key attributes of AUC as a highly effective technique for characterizing viral vectors for viral gene therapy delivery systems

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Development and Production of Viral Vectors: Advances in Processes and Translation for Human Gene Therapy

Duration: 46 minutes 34 seconds Understand the role viral vectors play in modern gene research and how ultracentrifugation is used to produce these key delivery systems

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Gallios Flow Cytometer Forward Angle Light Scatter Innovation

Duration: 50 minutes 19 seconds In flow cytometry, the FALS (Forward Angle Light Scatter) detector collects scattered light from a particle that intersects with a laser and delivers information roughly proportional to the size of the particle. Learn more about the unprecedented detection capabilities of the Gallios flow cytometer.

Diversity of Extracellular Vesicles and Their Cargo in Cell-To-Cell Communication

Duration: 1 hour 2 minutes 56 seconds Dr. Jan Lötvall discusses the study of extracellular vesicles and their relevance for cell-to-cell communication and how they have been implicated in several ways in disease progression. Understand the wide diversity of extracellular vesicles, with diverse morphology according to electron microscopy studies and difference in RNA and protein cargo according to bioinformatics analyses.

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Optimizing Quality Control Electronic Records for 21 CFR Part 11 Compliance

Duration: 45 minutes 58 seconds

In this video, Beckman Coulter Product Manager Tony Harrison covers quality control records and 21 CFR Part 11, manual and electronic SOPs, final product QC, cleanroom environmental monitoring records and QC instrumentation electronic records.

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