Biomek 4000 Automated Workstation

A compact liquid handler ideal for smaller laboratories and/or those new to automation. It helps standardize daily pipetting routines, maintain sample quality and generate repeatable, reliable results.

Ideal for low-throughput workflows
12 Deck positions
1 - 1,000 µL pipetting volume range
Multiple interchangeable single- and eight-channel pipetting tools & gripper

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Biomek 4000 Features

Versatile Workspace

Compact entry-level liquid handler fits on lab bench
Up to 12 deck positions
Add labware feeders to increase system capacity
Fits in laminar flow hood
Optional enclosure to protect samples from airborne particles
Configurable for specific applications

Flexible Pipetting & Workflow Management

On-the-fly interchangeable pipetting tools and gripper
Transfer volumes from 1 to 1000 µL
Liquid-level sensing
Supports labware from tubes to 384-well microplates
Execute accurate intra-well pipetting
Efficient wash and bulk dispense tool

Simple System Operation

Easily automate manual processes
Powered by icon-based software with data tracking and LIMS connectivity
Guided system setup
Factory-calibrated pipetting tools
Automated deck framing

Application-Focused Solutions

Consultative workflow analysis
Expert application & technical support
Biomek-automated demonstrated methods & capabilities for genomic, drug discovery & basic research workflows

Product Specifications

Sterile	No
Software	Biomek software, SAMI EX scheduling software, Biomek PowerPack software, Biomek Method Launcher, DART 2.0 software

Operating System	Windows^® 7
Display	22" controller screen
Operating Mode(s)	Semi-automated, manual, controlled by operator

Technical Documents

Documentation for Biomek 4000

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Title	Description
BeckmanConnect Installation and Activation Instructions {B14306BD-BB46-4B27-BF3E-B11862085BC7}	A step-by-step guide to help you successfully install BeckmanConnect.
Complete Solutions for your Specific Exosome Workflow from Preparation to Analysis {749D68FB-4893-4B2D-BD6C-C662F0520F64}	Beckman Coulter provides solutions customized for each step in your specific exosome research workflow – from sample preparation to sample analysis – and can also help improve processes and assist with related challenges.
BeckmanConnect Security Highlights {749D68FB-4893-4B2D-BD6C-C662F0520F64}	This document highlights the privacy and security features in the BeckmanConnect remote management solution.
Beckman Coulter Instrument PC Networking Requirements {749D68FB-4893-4B2D-BD6C-C662F0520F64}	This document describes the minimum technical criteria required to connect a Beckman instrument PC to a customer’s local network and/or the internet.
Biomek® NXP Laboratory Automation Workstation {A7DF4F56-8AF9-4BF1-88BE-766AB73FBC6B}	By incorporating a wide range of next-generation features into a smallfootprint design, Biomek NXP sets the standard for flexible laboratory solutions
Biomek® FXP Laboratory Automation Workstation {A7DF4F56-8AF9-4BF1-88BE-766AB73FBC6B}	The Biomek FXP is the latest entry in the Biomek line
Biomek-Automated NGS Library Construction Methods {AF33FD8F-E2CB-4E94-92EE-BF22B9B575AA}	DEMONSTRATED METHOD
Exosome Subclass Analysis {611E05FD-FC41-4E23-9498-DA5662F8D4F9}	Authors: Dr. Kiyotaka Shiba, Dr. Satoshi Yamamoto and Dr. Kazuya Iwai \| Tokyo Japan
Automation of PCR Reaction Setup and AMPure XP Purification Using the Biomek 4000 Workstation {C00ACFAF-8661-4DF6-8BA5-A7A099A7BA9C}	Authors: Ruth Zhang, Li Liu, Amy Yoder, John Palys, Bryan Daniels, Isabel Gautreau, William Godfrey Beckman Coulter, Inc., Indianapolis, IN, Danvers, MA, and Miami, FL
A Flexible Solution for Automating Cell Staining Using the Biomek 4000 Workstation {C00ACFAF-8661-4DF6-8BA5-A7A099A7BA9C}	Authors: Amy Yoder, Li Liu, William Godfrey - Beckman Coulter, Inc., Indianapolis, IN, and Miami, FL
Automation of PCR Reaction Setup and AMPure XP Purification Using the Biomek 4000 Workstation {C00ACFAF-8661-4DF6-8BA5-A7A099A7BA9C}	Both polymerase chain reaction (PCR) reaction setup and AMPure XP PCR reagent-mediated purification were automated on the Biomek 4000 Laboratory Automation Workstation.
A Flexible Solution for Automating Cell Staining Using the Biomek 4000 Workstation {C00ACFAF-8661-4DF6-8BA5-A7A099A7BA9C}	The automated Cell Staining Application on the Biomek 4000 Workstation can improve throughput and reproducibility of conventional staining of live and fixed adherent cells.
Automating a Linear Density Gradient for Purification of a Protein:Ligand Complex {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Author: Chad Schwartz, PhD, Application Scientist - Beckman Coulter, Inc., Indianapolis, IN USA \| Published 2014
g-Max: Added Capabilities to Beckman Coulter’s Versatile Ultracentrifuge Line {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Chad Schwartz, Ph.D., Application Scientist I \| Randy Lockner, M.S., Centrifugation Marketing \| Randy Pawlovich, Director of Product Management & Strategy \| Beckman Coulter, Inc., Indianapolis, IN USA
Automated Illumina TruSeq DNA PCR-Free Sample Preparation on the Biomek 4000 Laboratory Automated Workstation {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Author: David Horvath, M.S. \| Beckman Coulter, Inc.
Automated Sample Preparation for the Monitoring of Ethanol Metabolites in Urine by LC-MS/MS {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	In this application note, we describe an LC-MS/MS method for the analysis of EtG and EtS in urine employing a simple, automated sample preparation methodology using a liquid handling-based automation system.
Automated Sample Preparation for Cell-Based Assays {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	The automation of sample preparation and analysis workflows for a variety of common cellular assays.
Automation of NGS Sample Size Selection using SPRIselect {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	To streamline the NGS sample preparation process, Beckman Coulter has recently launched the SPRIselect Reagent Kit to allow NGS sample size selection to be automated on Biomek liquid handling platforms for high throughput and high efficiency sample preparations.
Automated Sample Preparation for the Monitoring of Pharmaceutical and Illicit Drugs by LC-MS/MS {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	This application note describes results obtained using a liquid handling-based automation system for the sample preparation of compounds to be analyzed by LC-MS/ MS and applied to the monitoring of multiple classes of pharmaceutical and illicit drugs.
Automated Liquid Handling for Cell Staining and Imaging {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Here we describe a variety of automated solutions to reduce the time, effort, and complexity associated with sample preparation workflows for cell imaging.
Automated Illumina TruSeq Nano DNA Sample Preparation on the Biomek 4000 Laboratory Automated Workstation {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Author: David Horvath, M.S. - Beckman Coulter, Inc. \| Published 2016
Reproducible and Efficient Automation of DTR Purification Using the Biomek 4000 Workstation and CleanSEQ {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	The Agencourt CleanSEQ* application for the Biomek 4000 Laboratory Automation Workstation is a rapid, high performance dye-terminator removal method utilizing Solid Phase Reversible Immobilization (SPRI) paramagnetic beadbased technology.
Reproducible and Efficient Automation of DTR Purification Using the Biomek 4000 Workstation and CleanSEQ {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Alexandra Scavo - Senior Applications Scientist, John Palys - Systems Engineer II, Beckman Coulter Life Sciences, Danvers, Mass., USA
High-Performance Exosome Purification and Characterization via Density Gradient Ultracentrifugation and Dynamic Light Scattering {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Exosomes purification and analyses comprise a fast evolving research area; more than 70% of published research on exosomes has been done within the last six years.
High-Performance Exosome Purification and Characterization via Density Gradient Ultracentrifugation and Dynamic Light Scattering {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Exosomes purification and analyses comprise a fast evolving research area; more than 70% of published research on exosomes has been done within the last six years
Automating a Linear Density Gradient for Purification of a Protein:Ligand Complex {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Author: Chad Schwartz, PhD, Application Scientist \| Beckman Coulter, Inc., Indianapolis, IN USA \| Published 2014
Mo Bio PowerMag Soil DNA Isolation Kit on Biomek 4000 Liquid Handling Automation {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Author: Shilpa Parakh, Beckman Coulter, Inc \| Published 2016
Automation of NGS Sample Size Selection using SPRIselect on the Biomek 4000 Laboratory Automation Workstation {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Ruth Zhang, Sr. Development Scientist, Li Liu, Sr. Development Scientist, Mary Blair, Sr. Applications Scientist, Amy Yoder, Staff Development Scientist, Alexandra Scavo, Sr. Applications Scientist, and William Godfrey, Sr. Manager Development Science, Beckman Coulter Life Sciences, Indianapolis, IN \| Published 2013
Reproducible and Efficient Automation of PCR Reaction Setup and Purification Using the Biomek 4000 Workstation and AMPure XP {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Ruth Zhang, Li Liu, Amy Yoder, John Palys, Bryan Daniels, Isabel Gautreau and William Godfrey Beckman Coulter Life Sciences, Indianapolis, IN \| Published 2013
Automation of Cell Staining Using the Biomek 4000 Laboratory Automation Workstation {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Manual cell staining of cardiomyocytes, either to characterize antigen expression or to assess cell health, is labor-intensive and time-consuming.
Enzymatic Determination Of Glycerol Contents In Biological Samples Using The Biomek 4000 Laboratory Automation Workstation {442DF88C-CA7F-4B78-AF75-9D2B985534C0}	Authors: Dr. Jörg Mampel, B.R.A.I.N Aktiengesellschaft, Darmstaedter Str. 34-36, D-64673 Zwingenberg \| Published 2014
Lab Automation Training Programs {9E29D7A5-B5EC-470A-A5C1-4EF9BFAE9959}	Real-world training options for maximizing the value of your Biomek liquid handling system.
Protection for your Workflows in Automation {9E29D7A5-B5EC-470A-A5C1-4EF9BFAE9959}	Maintenance service plan for Biomek liquid handlers
Biomek ® NXP Laboratory Automation Workstation {A7DF4F56-8AF9-4BF1-88BE-766AB73FBC6B}	It puts every aspect of liquid handling – including pipetting, dilution, dispensing and integration – into a single, automated system that is as powerful and flexible as it is efficient and economical.
Biomek ® FXP Laboratory Automation Workstation {A7DF4F56-8AF9-4BF1-88BE-766AB73FBC6B}	With an up-to-date hardware design for greater positional accuracy and increased robustness, it can meet the needs of just about any application.
Biomek 4000 Laboratory Automation Workstation {A7DF4F56-8AF9-4BF1-88BE-766AB73FBC6B}	From its enhanced worksurface with interchangeable tools to its flexible, icon-driven software, the Biomek 4000 system adapts to your ever-changing research needs.
Biomek-Automated NGS Library Construction Methods {A7DF4F56-8AF9-4BF1-88BE-766AB73FBC6B}	Next generation sequencing demonstrated methods